| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Away | Western Bulldogs | 14.13 97 | 17.11 113 | -16 | Docklands Stadium | 15/03/2025 | Match stats |
| R2 | Home | Melbourne | 19.11 125 | 9.12 66 | 59 | Docklands Stadium | 23/03/2025 | Match stats |
| R3 | Away | Adelaide | 12.6 78 | 17.12 114 | -36 | Adelaide Oval | 30/03/2025 | Match stats |
| R4 | Home | Sydney | 8.4 52 | 18.9 117 | -65 | Docklands Stadium | 05/04/2025 | Match stats |
| R5 | Home | Gold Coast | 13.11 89 | 21.15 141 | -52 | Barossa Park | 12/04/2025 | Match stats |
| R6 | Home | Carlton | 11.5 71 | 24.9 153 | -82 | Docklands Stadium | 18/04/2025 | Match stats |
| R7 | Away | Port Adelaide | 13.10 88 | 14.13 97 | -9 | Adelaide Oval | 26/04/2025 | Match stats |
| R8 | Away | Essendon | 9.8 62 | 9.11 65 | -3 | Docklands Stadium | 01/05/2025 | Match stats |
| R9 | Home | Brisbane | Bellerive Oval | 11/05/2025 | ||||
| R10 | Away | Richmond | MCG | 18/05/2025 | ||||
| R11 | Home | Collingwood | Docklands Stadium | 24/05/2025 | ||||
| R13 | Home | West Coast | Hands Oval | 08/06/2025 | ||||
| R14 | Home | Fremantle | Perth Stadium | 14/06/2025 | ||||
| R15 | Away | Carlton | MCG | 21/06/2025 | ||||
| R16 | Away | Hawthorn | York Park | 28/06/2025 | ||||
| R17 | Home | Western Bulldogs | Docklands Stadium | 04/07/2025 | ||||
| R18 | Away | Melbourne | MCG | 11/07/2025 | ||||
| R19 | Away | Sydney | SCG | 18/07/2025 | ||||
| R20 | Home | Geelong | Docklands Stadium | 25/07/2025 | ||||
| R21 | Away | St Kilda | Docklands Stadium | 01/08/2025 | ||||
| R22 | Away | GWS Giants | Manuka Oval | 08/08/2025 | ||||
| R23 | Home | Richmond | Bellerive Oval | 15/08/2025 | ||||
| R24 | Home | Adelaide | Docklands Stadium | 22/08/2025 |