| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R1 | Away | Collingwood | 6.9 45 | 21.10 136 | -91 | MCG | 15/03/2025 | Match stats |
| R2 | Home | Richmond | 21.14 140 | 9.14 68 | 72 | Adelaide Oval | 22/03/2025 | Match stats |
| R3 | Away | Essendon | 8.12 60 | 9.18 72 | -12 | Docklands Stadium | 27/03/2025 | Match stats |
| R4 | Home | St Kilda | 10.12 72 | 13.11 89 | -17 | Adelaide Oval | 06/04/2025 | Match stats |
| R5 | Home | Hawthorn | 18.13 121 | 14.7 91 | 30 | Adelaide Oval | 13/04/2025 | Match stats |
| R6 | Away | Sydney | 13.7 85 | 10.17 77 | 8 | SCG | 20/04/2025 | Match stats |
| R7 | Home | North Melbourne | 14.13 97 | 13.10 88 | 9 | Adelaide Oval | 26/04/2025 | Match stats |
| R8 | Away | Western Bulldogs | 5.11 41 | 20.11 131 | -90 | Eureka Stadium | 03/05/2025 | Match stats |
| R9 | Home | Adelaide | 12.12 84 | 13.11 89 | -5 | Adelaide Oval | 10/05/2025 | Match stats |
| R10 | Home | Geelong | 5.9 39 | 17.13 115 | -76 | Adelaide Oval | 17/05/2025 | Match stats |
| R11 | Away | Fremantle | 7.9 51 | 15.10 100 | -49 | Perth Stadium | 24/05/2025 | Match stats |
| R13 | Away | GWS Giants | 9.12 66 | 7.8 50 | 16 | Manuka Oval | 07/06/2025 | Match stats |
| R14 | Home | Melbourne | 14.9 93 | 9.14 68 | 25 | Adelaide Oval | 15/06/2025 | Match stats |
| R15 | Home | Sydney | Adelaide Oval | 21/06/2025 | ||||
| R16 | Home | Carlton | Adelaide Oval | 26/06/2025 | ||||
| R17 | Away | Brisbane | Gabba | 05/07/2025 | ||||
| R18 | Home | West Coast | Adelaide Oval | 13/07/2025 | ||||
| R19 | Away | Hawthorn | York Park | 19/07/2025 | ||||
| R20 | Away | Adelaide | Adelaide Oval | 26/07/2025 | ||||
| R21 | Away | Geelong | Kardinia Park | 03/08/2025 | ||||
| R22 | Home | Fremantle | Adelaide Oval | 09/08/2025 | ||||
| R23 | Away | Carlton | Docklands Stadium | 16/08/2025 | ||||
| R24 | Home | Gold Coast | Adelaide Oval | 22/08/2025 |