| Round | Type | Opponent | For | Against | Margin | Venue | Date | |
|---|---|---|---|---|---|---|---|---|
| R0 | Home | Hawthorn | 11.10 76 | 14.12 96 | -20 | SCG | 07/03/2025 | Match stats |
| R1 | Home | Brisbane | 12.10 82 | 12.14 86 | -4 | SCG | 15/03/2025 | Match stats |
| R2 | Away | Fremantle | 9.14 68 | 9.11 65 | 3 | Perth Stadium | 23/03/2025 | Match stats |
| R4 | Away | North Melbourne | 18.9 117 | 8.4 52 | 65 | Docklands Stadium | 05/04/2025 | Match stats |
| R5 | Away | Collingwood | 12.6 78 | 16.13 109 | -31 | Adelaide Oval | 11/04/2025 | Match stats |
| R6 | Home | Port Adelaide | 10.17 77 | 13.7 85 | -8 | SCG | 20/04/2025 | Match stats |
| R7 | Away | Gold Coast | 12.7 79 | 17.15 117 | -38 | Carrara Oval | 27/04/2025 | Match stats |
| R8 | Home | GWS Giants | SCG | 04/05/2025 | ||||
| R9 | Away | Essendon | Docklands Stadium | 10/05/2025 | ||||
| R10 | Home | Carlton | SCG | 16/05/2025 | ||||
| R11 | Away | Melbourne | MCG | 25/05/2025 | ||||
| R12 | Home | Adelaide | SCG | 31/05/2025 | ||||
| R13 | Away | Richmond | MCG | 07/06/2025 | ||||
| R15 | Away | Port Adelaide | Adelaide Oval | 21/06/2025 | ||||
| R16 | Home | Western Bulldogs | SCG | 28/06/2025 | ||||
| R17 | Home | Fremantle | SCG | 04/07/2025 | ||||
| R18 | Away | St Kilda | Docklands Stadium | 11/07/2025 | ||||
| R19 | Home | North Melbourne | SCG | 18/07/2025 | ||||
| R20 | Away | GWS Giants | Sydney Showground | 25/07/2025 | ||||
| R21 | Home | Essendon | SCG | 01/08/2025 | ||||
| R22 | Away | Brisbane | Gabba | 08/08/2025 | ||||
| R23 | Home | Geelong | SCG | 15/08/2025 | ||||
| R24 | Away | West Coast | Perth Stadium | 22/08/2025 |